Animal Science Research Institute of Iran (ASRI), Agricultural Research, Education and Extension Organization (AREEO), Karaj, Iran
Abstract: (72 Views)
Diseases caused by viral and bacterial pathogens represent major challenges to global aquaculture, threatening productivity and sustainability. Conventional disease management strategies such as vaccines and antibiotics have limitations including specificity and resistance development. Molecular biotechnology offers revolutionary tools to enhance disease resistance in aquatic animals through genomic selection, gene editing, and molecular immunomodulation. This review comprehensively examines the application of molecular biotechnology in improving immune defenses against viral and bacterial infections in aquaculture species. Key technologies including omics, CRISPR/Cas systems, antimicrobial peptides, and RNA interference are discussed. Immunological mechanisms of aquatic species, advances in selective breeding, and emerging precision aquaculture approaches are reviewed. Challenges and future perspectives are highlighted to provide a roadmap for sustainable aquaculture disease management using molecular biotechnology.
Nahavandi R, Pourmozaffar S. The Role of Molecular Biotechnology in Enhancing Immune Resistance of Aquatic Species Against Viral and Bacterial Diseases. Journal title 2025; 1 (1) :1-17 URL: http://injbr.com/article-1-21-en.html