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A review of the potentials and challenges of developing a vaccine for prevention of acute hepatopancreatic necrosis disease in shrimp
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Mohammad Sheikh Asadi   , Mohsen Gozari |
| Persian Gulf and Oman Sea Ecology Research Center |
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Abstract: (41 Views) |
Acute hepatopancreatic necrosis disease (AHPND) is a deadly infectious disease in the shrimp that has devastating impact on the shrimp aquaculture industry. The resistance of shrimp to invading pathogens depends on the immune status of the host. Although the defense mechanisms of crustaceans are less mature than those of teleosts and other vertebrates and lack true immune memory, there is increasing evidence that shrimp and some arthropods have a specific and memory-like immunity. This type of immune response, which is observed in invertebrates, is known as "specific innate immunity". However, a better understanding of the precise mechanisms of the shrimp defense system can help improve disease management and treatment strategies in the shrimp farming industry. Since the use of antibiotics in aquaculture has been banned in many countries, farmers are looking for alternative methods to prevent diseases. One of these methods is to strengthen the shrimp immune system through a type of "vaccination" that has been studied to combat various diseases, including the bacterial disease vibriosis and acute hepatopancreatic necrosis of shrimp. This article reviews studies and the possibility of developing a shrimp vaccine.
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| Keywords: Acute hepatopancreatic necrosis disease, Dscam, Immune system, Shrimp farming, Vaccine |
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Full-Text [PDF 1058 kb]
(24 Downloads)
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Type of Study: Applicable |
Subject:
Special
Received: 2025/10/21 | Accepted: 2025/10/2 | Published: 2025/10/2
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